Red Blood Cells

Population dynamics of red blood cells

Jan 2011

Higgins and Mahadevan analyzed data on red cells and derived an equation model of red-cell maturation and clearance. They observed that the threshold for clearance is lowered with iron-deficiency anemia and thalassemia trait and showed how their model can differentiate these two disorders.

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Related Publications

Physiological and pathological population dynamics of circulating human red blood cells J. Higgins and L. Mahadevan,  Proceedings of the National Academy of Sciences , 107, 20587-92, 2010. [View PDF] [Download PDF]
Pressure-driven occlusive flow of a confined red blood cell T. Savin, M. M. Bandi and L. Mahadevan,  Soft Matter , 12, 562-573, 2015. [View PDF] [Download PDF]
Statistical dynamics of flowing red blood cells by morphological image processing J. Higgins, D. Eddington, S. Bhatia and L. Mahadevan,  PLoS Computational Biology , 5, e1000288, 2009. [View PDF] [Download PDF]