8-cell embryo, three days after fertilization (WikiCommons)

How early-stage embryos maintain their size

Aug 2019

Mechanical cues play critical role in shaping form and function

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Related Publications

Hydraulic control of mammalian embryo size and cell fate
C.J. Chan, M. Costanzo, T. Ruiz-Herrero, G. Monke, R. Petrie, L. Mahadevan, T. Hiiragi, Nature 571, 112–116, 2019. [DOI] [View PDF] [Download PDF]
Molecular control of macroscopic forces drives formation of the vertebrate hindgut N.L. Nerurkar, CH Lee, L. Mahadevan & C.J. Tabin, Nature 565, 2019. [DOI] [View PDF] [Download PDF]