Protein Clumping Best Blocked Using Specific Compounds at Distinct Disease Stages, Model Suggests

Aug 2019

A mathematical model created to more effectively prevent protein clumping, widely thought to underlie diseases like Parkinson’s, found that different potential treatments work best at different disease stages

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Optimal strategies for inhibition of protein aggregation T.C. Michaels, C. Weber and L. Mahadevan, PNAS 116 (29) 14593-14598, 2019. [View PDF] [Download PDF]